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FIGURE 4. Complementary information on tumor activity and extent as depicted by multimodal imaging in 2 patients with tumors near midline. (A) A 57-y-old woman with recurrent WHO grade III oligoastrocytoma in thalamus. Whereas area of gadolinium enhancement is small, 11C-MET and 18F-FLT PET are suggestive of gross involvement of thalami on both sides. (B) A 39-y-old woman with recurrent astrocytoma within vermis and extension into midbrain and thalamus. Gadolinium enhancement is mainly restricted to vermis, whereas 11C-MET and 18F-FLT uptake show clear involvement of left-sided midbrain and thalamus.