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FIGURE 1. Two patients with highly intense 18F-FLT accumulation that was found mainly in areas of breakdown of blood–brain barrier as depicted by gadolinium-enhanced MRI. A 64-y-old man with newly diagnosed glioblastoma (A) and 26-y-old woman with newly diagnosed WHO grade I astrocytoma (B). In both patients, 11C-MET PET is suggestive of a larger extent of tumor as depicted by gadolinium MRI.





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