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FIGURE 2. Coronal images (from left to right, MRI, composite SISCOM, and composite subtraction SPECT) and rainbow color scale for anterior (top) and posterior temporal (bottom) regions of left MTLE group. At far right is composite subtraction SPECT image of MTS subgroup, matched to same MRI plane as left MTLE group. Anterior section shows that all temporal lobe gyri are significantly hyperperfused, with extension into basal ganglia and insula. Much of anterior temporal lobe of left MTLE group shows composite intensity value of 15 (represented by purple, P < 0.0001). Contralateral temporal lobe and basal ganglia are significantly hyperperfused in anterior section. Posterior temporal region shows significant regions of hyperperfusion, but with most of temporal lobe showing perfusion changes near the cutoff value for significance. Contralateral mesial temporal region also shows significant hyperperfusion.