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FIGURE 6. Survival analysis of TXM13 human melanoma-bearing SCID mice. Kaplan–Meier survival curves for TXM13 human melanoma-bearing mice treated with 22.2 MBq ({blacktriangleup}), 2 x 14.8 MBq ({blacksquare}), and 37.0 MBq ({blacktriangledown}) of 188Re-(Arg11)CCMSH or saline placebo ({square}). Mean survival time was 39.6 ± 15.0 d for untreated control group, 41.4 ± 10.9 d (P > 0.05) for 2 x 14.8-MBq treated group, 57.6 ± 24.2 d (P < 0.05) for 22.2-MBq treated group, and 72.7 ± 18.3 d (P < 0.05) for 37.0-MBq treated group.





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