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FIGURE 5. Measured residual uptake using various ROIs keeping tumor uptake constant. Max = maximum pixel value; 50% = ROI50; 70% = ROI70; 0.5BGM = ROI0.5(BG+MAX); 15x15 = ROI15x15. (A and B) No smoothing of image. (C and D) Smoothing of image. A and C represent tumor data with TBR = 2; B and D represent tumor data with TBR = 8. Reduction of diameter to 10, 15, and 20 mm and not at all (it stays 30 mm) is shown from left to right in each set of 4 bars. Missing bars in this figure correspond to missing data due to impossible ROI definition—that is, ROI enclosed entire patient.
