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FIGURE 4. Measured residual uptake using various ROIs for simulated tumors showing a decrease in uptake only. (A and B) Nonsmoothed data. (C) Smoothed data. A and C give response of tumors with constant tumor size of 10-mm diameter; B and D show response of tumors with constant tumor size of 30 mm. Residual uptake was measured using maximum pixel value, ROI50, ROI70, ROI0.5(BG+MAX), and ROI15x15 as shown from left to right in each set of 5 bars. Error bars represent 1 SD. Missing bars in this figure correspond to missing data due to impossible ROI definition—that is, ROI enclosed entire patient.
