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FIGURE 2. Illustration of SKA-M for 1 field of view. Both axes are similar to regular Patlak analysis except that a population input function, Apop(t), is used for A(t). Ameas(t) is determined as in Equation 2. One-level SKA-M requires only a few late time points (in this case between 25 and 55 min after injection). The regular Patlak analysis requires a full dynamic acquisition from the time of injection to about 60 min. Two-level SKA-M uses only every other point at each field of view, whereas 3-level SKA-M uses every third point from 10 min to 
55 min (not shown).
