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FIGURE 1. Preoperative HBS in patient 13, with a proximal cholangiocarcinoma. (A) Reframed images of the dynamic acquisition. Homogeneous liver uptake with moderate cholestasis is seen in the left side, without functional repercussion. (B) A summed image from 150 to 350 s after intravenous injection of 80 MBq of 99mTc-mebrofenin, with an ROI drawn semiautomatically (threshold, 20%) around the entire liver and a second ROI drawn in the mediastinum (blood pool). (C) A blood-pool–corrected liver-uptake time–activity curve. Liver uptake (d) is calculated as the increase in specific (corrected for blood pool) 99mTc-mebrofenin uptake (y-axis) per minute over a period of 200 s (x-axis).
