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FIGURE 7. Modeling of response of labeled cells to combined effects of self-doses and cross-doses when 50% of cells are labeled with 131IdU. Self-dose is given by bottom axis, whereas cross-dose is given by top axis. Self-dose to cross-dose ratio is 0.24 for 50% labeling when 131I is in cell nucleus (131IdU). Experimental data for 2 independent experiments (A and B) are shown separately (•, 
). Errors bars represent SDs of mean survival fraction based on triplicate samples. Solid line represents survival fraction predicted by model SFlabeled = e–Dself/D37,selfe–Dcross /D37,cross, where D37,self and D37,cross are 1.2 and 4.0 Gy, respectively.
