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FIGURE 5. Survival of V79 cells in multicellular clusters as function of absorbed dose to cell nucleus. Multicellular clusters were formed with equal numbers of cells labeled with 131IdU and unlabeled cells. Labeled cells ({blacksquare}) received both self-doses and cross-doses, whereas unlabeled cells ({square}) received only cross-dose. Data shown are pooled from Figures 3A and 3B. SDs of mean survival based on triplicate samples are indicated by error bars. Least-squares fits of data to an exponential dose– response function are shown for labeled (solid line) and unlabeled (dashed line) cells. Corresponding D37 values are given in Table 1.





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