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FIGURE 3. Survival of V79 cells in multicellular clusters as function of initial 131I activity per labeled cell. Multicellular cluster contained 50% cells labeled with 131IdU. Data are shown for 2 independent experiments (A and B) and separately for labeled (,
) and unlabeled (
,
) cells. Survival fractions for labeled and unlabeled cells were determined compared with dyed and undyed cells, respectively, taken from control clusters (50% dyed with CFDA-SE and 50% undyed). SDs of mean survival based on triplicate samples are indicated by error bars. Least-squares fits of data to an exponential function are represented by solid (labeled) and dashed (unlabeled) lines, respectively. These fits are provided only to emphasize differences in doseresponse between labeled and unlabeled cells.