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FIGURE 8. Relationships between mHSV1-TK enzyme activity assessed in vitro and compartmental modeling results (using 3-compartment model shown in Fig. 2). 
, Data points obtained in each individual rat infected with Ad-CMV-mNLS-HSV1sr39tk-egfp (n = 7). •, Data points obtained in 2 animals infected with control virus (n = 2). Ki (influx constant) represents net uptake of tracer into irreversibly bound compartment. K1 and k3 are individual rate constants shown in Figure 2. PCV = penciclovir.
