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FIGURE 5. 18F-FDG PET images of vascular dementia. Hypometabolism affecting cortical, subcortical, and cerebellar areas is often seen in vascular dementia. This patient (65-y-old woman) was followed for 10 mo, and vascular dementia was diagnosed both clinically and by structural imaging. Arrows indicate hypometabolism of the right frontal cortex (far left, middle right), right parietal cortex (far left, middle left), right basal ganglia and thalamus (middle right), and right temporal cortex (far right). The hypometabolism of the left cerebellum (far right) is characteristic of cross-cerebellar diaschisis, caused by diminished afferent input from the contralateral cortex.