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FIGURE 3. 18F-FDG PET images of early- and late-stage dementia with Lewy bodies. Typical cerebral metabolic patterns for patients with dementia with Lewy body disease are similar to AD patterns, but with less sparing of the occipital cortex. A patient with early-stage disease (top row; 63-y-old woman) was clinically followed up for 28 mo, during which her MMSE score dropped from 23 to 14, of 30 possible points. The arrows on her scan highlight bilateral hypometabolism of the parietal (left) and occipital (middle) cortices, as well as hypometabolism of the posterior temporal cortex (right). A patient in a later stage of the disease (bottom row; 71-y-old man) has moderate to severe bilateral hypometabolism in the parietal cortex (left) and in the temporooccipital cortex (right), as similarly seen in the early-stage patient. Additional arrows in the left image refer to progression of hypometabolism in the occipital and prefrontal cortices, bilaterally.
