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FIGURE 2. 18F-FDG PET images of early AD. Early Alzheimer’s typically affects the parietal, temporal, and posterior cingulate cortices. Brain images of this 80-y-old woman demonstrate hypometabolism of the parietal cortex, bilaterally (left and middle), with relative sparing of the primary visual cortex, sensorimotor cortex, thalamus, and basal ganglia. In the early stages of AD, deficits often appear asymmetrically, as evidenced here by mild hypometabolism of the left temporal cortex (right). In later stages of the disease, degeneration will be apparent bilaterally.
