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FIGURE 2. Imaging of hNIS gene transfer using 99mTcO4- and 
-camera scintigraphy. (A) Upper panel demonstrates the positive correlation between cpm per well and Ad-hNIS viral titer. Lower panel shows -camera images with increasing signal as adenovirus titer is increased. (B) Upper panel demonstrates the high correlation between cpm per well and activity of added 99mTcO4-. Line shows linear regression of cpm per well vs. 99mTcO4- activity. Lower panel shows -camera images of Ad-hNIS-infected MB-435 cells. Signal increased with increasing activities of 99mTcO4- at a fixed viral titer. Data are expressed as the mean ± SD of 3 replicates and are representative of at least 3 separate experiments.
