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FIGURE 1. 99mTc-TRODAT-1 SPECT images of 4 subjects. (A) A 62-y-old female healthy volunteer. (B) A 63-y-old female patient (H–Y stage I) with left side tremor and bradykinesia. The binding of 99mTc-TRODAT-1 decreased significantly in the right striatum and was also slightly reduced in the left putamen. (C) A 62-y-old female patient (H–Y stage III) with bilateral bradykinesia, dominant in the left side. The uptake decreased significantly in the bilateral putamen and was also slightly reduced in the bilateral caudate nuclei. The reduction was more severe in the right striatum. (D) A 63-y-old male patient (H–Y stage V) with severe bilateral akinesia. The uptake decreased in all defined regions.
