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FIGURE 1. Brain areas characterized by reduced rCMRgl in AD patients compared with healthy control subjects. Results (black blobs) are displayed as SPM projections in the 3 orthogonal right sagittal, posterior coronal, and superior axial views. Results are displayed at P < 0.001 (A) and P < 0.005 (B), uncorrected for multiple comparisons. Local maxima of these brain regions can be found in Table 2. (C) White spheres corresponding to the left EC (x = -20, y = -14, z = -20) and right EC (x = 18, y = -13, z = -16) are displayed on the coronal and axial slices of a spatially standardized MR image (left) and an 18F-FDG PET image (right). Axial slices are shown at z = -18 mm relative to the AC–PC line and coronal slices are shown at y = -13 mm relative to the origin. Corresponding local maxima are reported in Table 2.
