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FIGURE 3. Frequency histograms of GMR (A and B), WMR (C and D), and GCV (E and F) for uncorrected (PET) and corrected (M, MG, R, mMG) values. Data are plotted for the results of validation on the full dataset ([A, C, and E] misregistration
6 pixels; FWHM estimate ranging from -16.9% to 26.8% of the optimal value; GM volume changes resulting from segmentation error ranging from -13.7% to 14.1%) and on the dataset derived by the introduction of a reduced span of errors ([B, D, and F] misregistration
4 pixels; FWHM estimate between -12.0% and 16.3% of the optimal value; GM volume changes resulting from segmentation error between -5.3% and 5.5%).