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FIGURE 1. (A) A late cardiac planar 123I-MIBG image obtained from a 60-y-old female with congestive heart failure who had fatal pump failure. She had a persistently depressed LVEF (16%) and a highly increased plasma BNP level (1,070 pg/mL). Her late HMR (1.49) was markedly reduced. (B) A late cardiac planar 123I-MIBG image obtained from a 66-y-old male with congestive heart failure who survived. In response to drug therapy, he has an LVEF of 62%, a plasma BNP level of 76 pg/mL, and a normally preserved late HMR (2.14) at discharge. The box and oval indicate regions of interest on the upper mediastinal and cardiac areas, respectively, for calculation of the HMR of 123I-MIBG activity.