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FIGURE 2. Image artifact in contrast-enhanced PET/CT studies. Bolus passage of intravenous contrast agent in left subclavian and brachiocephalic veins on CT (A, arrows) led to areas of apparently increased glucose metabolism on corrected PET (B, arrows). On fused PET/CT images, this area of apparently increased glucose metabolism correlated with high-density contrast in venous system on CT (C). PET image reconstruction without attenuation correction demonstrated homogeneous tracer distribution (D), demasking areas of apparently increased glucose metabolism as artificial.