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FIGURE 7. Blockade of CD4+ cell migration to colon after anti-{alpha}4 antibody injection. Ex vivo planar scintigraphic images of isolated cleaned colon show distinct colon radioactivity uptake in mouse with TNBS colitis transferred with sensitized 111In-labeled CD4+ lymphocytes (A). Colon radioactivity uptake is decreased after treatment with anti-{alpha}4 antibody (B). Images are representative of 5 mice per group.





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