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FIGURE 2. Increased radioactivity on SPECT of mice with TNBS colitis mice transferred with TNBS-sensitized 111In-labeled lymphocytes. SPECT was performed 48 h after transfer of 111In-labeled TNBS-sensitized or nonsensitized lymphocytes to TNBS and saline control mice. Transverse slices from abdominal region at pelvic level are shown; amount of 111In uptake is color coded from low (black) to high (white). Four images are representative of 4 groups (donor–acceptor). (A) Colon uptake is low in NaCl–NaCl mouse. (B) Colon uptake is equivocal in TNBS–NaCl mouse. (C) Colon uptake is equivocal in NaCl–TNBS mouse. (D) Colon uptake (arrow) is manifest in TNBS–TNBS mouse.
