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FIGURE 1. Colon radioactivity uptake is increased in mice with TNBS colitis transferred with TNBS-sensitized 111In-labeled lymphocytes. SPECT was performed 48 h after transfer of 111In-labeled TNBS-sensitized or nonsensitized lymphocytes to TNBS and saline control mice. Colon uptake was calculated normalized to bone marrow uptake in pelvis and corrected for background activity: (colon – background)/(bone marrow – background). Box plots of mean radioactivity uptake in 4 groups are shown (donor–acceptor). Overall comparison, P = 0.002; individual comparison between TNBS–TNBS group and 3 other groups, **P = 0.004 (statistically significant).
