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FIGURE 6. Absorbed dose as function of radial position r in 1-g tumor (diameter, 1.24 cm) containing 37 MBq (1 mCi) of uniformly distributed 111In (thin solid line). Bold vertical lines denote boundaries between tumor (-0.62 < r < 62 cm) and normal tissue (-1.5 < r < -0.62 and 0.62 < r < 1.5 cm). Note precipitous drop in absorbed dose as one moves from tumor to normal tissue. Calculations were performed using methods described by Howell et al. (34). Also shown are dose profiles for 177Lu (bold solid line) and 90Y (dashed line). Profiles for these radionuclides correspond to injected activities (4.67 MBq [0.126 mCi] and 2.22 MBq [0.060 mCi], respectively) that deliver, on complete decay, same dose to center of tumor as 37 MBq (1 mCi) 111In (96.2 Gy [9,620 rad]).
