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FIGURE 3. (A) Schematic diagram of tumor, needle, and sections of tumors cut in perpendicular to path of needle. Two autoradiographs show 2 separate 20-µm-thick sections of tumor into which 111In was injected through sprinkler needle (D) and that of tumor that was injected with regular needle (C). Tumor injected with sprinkler needle has spread over larger portion of tumor than that injected with regular needle. Because of tumor necrosis (B), even with sprinkler needle, 111In uptake in tumor is patchy and there is no 111In in center. Necrotic tissue can be seen (lightly stained part) in histologic section of tumor (B).
