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FIGURE 2. Precise localization of increased 18F-FDG uptake and exclusion of malignancy, after PET/CT. A 68-y-old man, 3 y after partial gastrectomy for adenocarcinoma of stomach, was referred for 18F-FDG PET/CT for further evaluation of polypoid mass in gastric stump detected on routine follow-up gastroscopy, with equivocal biopsy results. (A) 18F-FDG PET coronal images (top) and axial images (bottom) show increased 18F-FDG uptake in region of stomach (arrow). (B) Hybrid PET/CT axial image (top) precisely localizes and defines uptake as physiologic activity at gastric stump (arrowhead). Suspicious polypoid mass in anastomotic region (arrow), seen on corresponding hybrid and CT slices (bottom) obtained during same acquisition, shows no uptake of 18F-FDG. Findings on PET/CT were interpreted as physiologic 18F-FDG uptake in stomach and nonviable residual mass. Patient showed no evidence of disease for follow-up of 7 mo.