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FIGURE 2. Coronal T2-weighted MR image (A) shows enlarged isointense area of endometrium (arrow), indicating presence of tumor. Arrowhead points to intestine. This patient was diabetic. Blood sugar levels were 177 mg/dL (9.8 mmol/L) and 188 mg/dL (10.4 mmol/L) at time of 18F-FDG PET and 11C-choline PET, respectively. In 18F-FDG PET image (B), tumor uptake is negative in presence of hyperglycemia. 11C-Choline PET image (C) demonstrates increased tracer uptake (arrow), corresponding to endometrial tumor. 11C-Choline accumulation in bladder was only minimal, but small hot spot was seen in intestine (arrowhead). Surgical histologic examination revealed clear cell carcinoma (stage IB). BL = bladder activity.