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FIGURE 3. Inhibition of hSGLT1-expressed MDG uptake by compounds 5a, 5b, and 5c. Xenopus oocytes expressing hSGLT1 were incubated for 1 h with Ori buffer with or without 100 µmol/L phlorizin plus 10 µmol/L ¹⁴C-MDG and indicated concentrations of compound 5a, 5b, or 5c. Mean values ± SD of phlorizin-inhibited uptake rates measured from pairs of 7–10 oocytes are presented. Michaelis-Menten equation was fitted to data.

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