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FIGURE 1. A 75-y-old woman after resection of rectal carcinoma. Before PET, curative radiotherapy was planned. Coronal (A) and transverse (B) PET scans show previously unknown iliac internal lymph node metastasis (arrow). Correlating CT scan (C) does not show any metastases. Therapy concept was changed from curative to palliative treatment concept. Therefore, no irradiation but chemotherapy was given. After chemotherapy, PET was performed for restaging. Disappearance of abnormal 18F-FDG accumulation confirmed lymph node metastasis in initial PET study.