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FIGURE 3. Typical set of time–activity curves in putamen ({blacktriangleup}), thalamus ({blacksquare}), and cerebellum (•) with fitted curves (solid lines) obtained in healthy human volunteer. Dashed lines represent specific binding in putamen (long dashes) and in thalamus (short dashes), when specific binding in these structures is expressed as difference between total binding in structure and cerebellum. From 3-compartment, 5-parameter model, rate constants in putamen in this subject were determined as follows: K1 = 0.405 mL/min/mL; k2 = 0.077/min; k3 = 0.862/min; k4 = 0.338/min.





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