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FIGURE 2. PET left ventricular time-activity curve after injection of 9.9-nmol dose of 11C-S12968, followed 20 min later by injection of 8.8 nmol, followed 20 min later by injection of 10.1 nmol. Time-activity curve is characterized by low noise contribution. Quality of fit of experimental data to 3-compartment mathematic model is satisfactory. DATA = data from experiment 3; MODEL = 3-compartment mathematic model.





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