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FIGURE 3. Immunohistochemical staining and 131I whole-body scan findings of patient with papillary carcinoma. (A and B) In immunohistochemical staining for NIS (x200), NIS protein was not detected in paraffin block sections of either primary tumor (A) or lymph node (B). (C) Whole-body scan obtained 5 d after ingestion of 1.11 GBq 131I shows no metastatic site; remnant thyroid activity is also shown (arrow). (D) 18F-FDG PET scan obtained 3 wk later shows abnormally increased 18F-FDG uptake on right side of neck and in mediastinum (arrowheads). (Reprinted with permission of (37).)
