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FIGURE 4. PET and SISCOM abnormalities in ipsilateral and contralateral frontal and perisylvian regions ({blacksquare}, PET and SISCOM abnormalities; , PET abnormalities alone; {square}, SISCOM abnormalities alone). (A) Orbitofrontal gyri and gyrus rectus. (B) Frontal pole and prefrontal cortex. (C) Insular gyri. (D) Cingulate gyrus. Note marked involvement of ipsilateral and contralateral orbitofrontal gyrus (A) and insular cortex (C) with high rate of concordance between PET and SISCOM. In cases of spreading functional changes, SISCOM abnormalities were more frequent (B and D).





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