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FIGURE 1. Paired nucleoside accumulation studies in RG2TK+ transduced cells. (A) 18F-FHBG-14C-FIAU (
) and 18F-FHPG-14C-FIAU (
) accumulation data (mL medium/g cells) are shown. (B) 18F-FHBG-14C-FIAU and 18F-FHPG-14C-FIAU comparisons with 3H-TdR are shown: 14C-FIAU (), 18F-FHBG (
), and 18F-FHPG (
). Each point represents paired comparison of uptake results obtained from single triple-label experiment; experimental times varied between 10 and 180 min.
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