FIGURE 3. Light microscopic study of bFGF localization in AßPP Tg mouse cortex, with and without intranasal bFGF injection. bFGF is not readily detectable in neurons in Tg(-) mice after receiving bFGF intranasally (A) or in Tg(+) mice without bFGF injection (B). (C) Nasally injected bFGF bound to cytoplasm of neurons around Aß deposits in frontal, parietal, and occipital regions in Tg(+) mice. Scale bar = 50 µm.

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