Click on image to view larger version.

FIGURE 2. Uptake kinetics of 125I-B72.3 by LS174T xenografts in athymic mice treated intravenously with one 0.1-mg dose of AP at indicated time points before administration of 125I-B72.3. For example, 3 h on x-axis indicates that AP was administered 3 h before dose of radiotracer. Biodistribution was conducted 72 h after injection of 125I-B72.3. Data are expressed as average ± SD (*3-h vs. 6-h uptake, P > 0.2 at 0.05 level of significance; **3-h vs. 24-h uptake, 0.05 > P > 0.02 at 0.05 level of significance).