FIGURE 4. Brain uptake, expressed as %ID/g brain, at 1, 2, 4, and 6 h after intravenous injection of ¹²⁵I-HD-PNA-8D3 conjugate is shown. Data are mean ± SE (n = 3 mice per group). Linear regression analysis yielded intercept (Int.) and slope values that are shown. PNA-8D3 conjugate underwent export from brain back to blood with t_1/2 of 4.3 ± 0.5 h.

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