FIGURE 3. BBB permeability-surface area (PS) product, AUC, and brain uptake, expressed as %ID/g brain, is shown for either unconjugated ¹²⁵I-HD-PNA or ¹²⁵I-HD-PNA-8D3 conjugate. Data are mean ± SE (n = 3 mice per group). Units of PS product are µL/min/g and units of 60-min plasma AUC are %ID·min/mL.

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