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FIGURE 1. A 51-y-old woman with approximately 19-mm palpable lesion of left breast. Craniocaudal mammogram showed probable malignancy (A, arrow). Scintimammograms are displayed in lateral views. Early sestamibi scan at 10 min (B) and delayed sestamibi scan at 1 h (C) showed clear, focal lesion in left breast (true-positive finding). Early MDP scan at 10 min (D) also showed focal uptake in left breast, reported as positive finding and diffuse activity. Early DMSA-V scan at 10 min (E) and delayed DMSA-V scan at 2 h (F) showed focal and diffuse uptake in left breast, reported as positive finding for early scan. Compared with other 2 radiopharmaceuticals, sestamibi showed net focal uptake and almost no contralateral activity. Histopathology showed ductal infiltrating carcinoma in left breast, with 11 of 19 lymph nodes in left axilla positive for cancer. HORA = hour.





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