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FIGURE 2. Depiction of cortical areas showing significant rCBF increase with STN stimulators on (DBS on) in comparison with preoperatively (pre-DBS) and postoperatively with STN stimulators off (DBS off). STN stimulation induced rCBF increases in motor (right pre-SMA), associative (DLPFC and medial BA8), and limbic (ACC) areas of frontal lobes in living brain of 10 parkinsonian patients. (A) Results are displayed as SPM projections in 3 orthogonal views, with cutoff of P < 0.05 corrected for multiple comparisons. (B and C) Plots of mean and individual adjusted rCBF values during preoperative (pre-DBS) and postoperative (DBS on and DBS off) conditions are depicted for right pre-SMA (B) and, bilaterally, for ACC, DLPFC, and medial BA8 (C).





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