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FIGURE 2. Mebrofenin imaging shows kinetics of hepatic mebrofenin uptake and excretion in representative rats. Sequential images from same animal are shown. (A) LEA rat shows prompt mebrofenin clearance from liver, such that at 20 min after mebrofenin injection, significant amount of activity had cleared. (B) LEC rat shows considerably longer retention of mebrofenin activity in liver. In this animal, exceptionally large amount of activity was present in liver even at 60 min after mebrofenin injection. Arrowhead indicates splenic site of mebrofenin injection.





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