FIGURE 4. Example of PET time–concentration curves obtained with mini pigs using multiinjection protocol. Experimental data obtained in experiment 7 (Table 1 shows timing and injected doses) in myocardium are represented by 
. Solid line, which is simulated curve obtained from estimated model parameters (Table 2), is close to experimental data. This proves quality of fit obtained using 3-compartment model. PET-measured concentrations in cavity (
) are good estimates of blood concentration measured by sampling (dotted line) during first 10 min after injection. After this period, low concentration and heart movements lead to noisy data.
