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FIGURE 7. 99mTc-annexin V uptake (A) vs. nonspecific 125I-BSA uptake (B) within representative rear paws of arthritic and age-matched control mice. Mice were sacrificed 1 h after tail vein injection of 37–55 MBq (1–1.5 mCi) of 99mTc-annexin V. Frozen sections (50 µm) were obtained and exposed overnight on tritium phosphor screen. Screens were then read out with resolution of 50 µm. Five days later, after complete decay of 99mTc activity, same sections were placed on fresh tritium phosphor screen for 1 wk to determine 125I activity. Screens were then read out with resolution of 50 µm.
