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FIGURE 5. Representative time course of 99mTc-annexin V uptake in hind paws of representative mice: 1 with untreated arthritis at week 2 (A), 1 with untreated arthritis at week 3 (B), 1 with untreated arthritis at week 4 (C), 1 control (D), and 1 with steroid-treated arthritis (E). Mice were sacrificed 1 h after tail vein injection of 37–55 MBq (1–1.5 mCi) of 99mTc-annexin V. Frozen sections (50 µm) were obtained and exposed overnight on tritium phosphor screen. Screens were then read out with resolution of 50 µm.
