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FIGURE 5. Plot of ${partial}$ Ki/ ${partial}$ ${lambda}$ k₃( ${lambda}$ k₃/Ki) vs. ${lambda}$ k₃ for K₁ values of 0.25, 0.50, 1.0, 1.5, 2.0, and 2.5 mL/min/mL. Note that when Ki changes very little with relatively large changes in ${lambda}$ k₃, uptake is flow limited. With larger values of K₁, Ki is sensitive to changes in ${lambda}$ k₃ over much wider range than for lower values.

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