FIGURE 3. (A) Axial slice from one CT image of pig with surgically induced LAD coronary artery occlusion shown with endocardial and epicardial borders drawn. Cross section through ventilation tube is visible in lower left corner of CT image. (B) Myocardial region of interest, or template, derived from CT image. (C) Reconstructed template image obtained after mathematically modeling SPECT acquisition process. (D) Corresponding ^99mTc-sestamibi image shows severe anteroseptal perfusion defect.

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