FIGURE 5. images 4 d after injection of ¹²⁵I-labeled MAb against keratan sulfate in animals with both lumbar and tail disk injuries (injuries are 2 d old on left, 7 d old in middle, and 17 d old on right). Increased uptake in lumbar lesion in animals with 7- and 17-d-old injuries (solid arrows) is best seen in middle in lower back. Lesion size was approximately 2 x 2 mm. Similarly, tail disk injuries are localized in animals with 7- and 17-d-old injuries (solid arrows). Injection sites are seen (open arrows) in these animals and make tail uptake diffuse in animal with 7-d-old injury (no arrows). In animal with 2-d-old injury, lesions show no uptake. Tracheas were also visualized but, unfortunately, are masked here by high thyroid uptake because these animals were not blocked for thyroid.

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