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FIGURE 6. {gamma}-Scintigrams of human tumor xenografts expressing different levels of EGFR. Mice with A431 (A), MDA-MB-468 (B), or MDA-MB-435 tumors (C) received 10 µg per mouse of 1:30 111In-DTPA-PEG-C225 intravenously. Images were acquired 24 h after radioligand injection. A431 (A) and MDA-MB-468 tumors (B; arrowheads) are more readily visualized than MDA-MB-435 tumors (C; arrowheads). Anterior views of mice placed prone on camera’s pinhole collimator, with heads pointing to top.





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