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FIGURE 1. Compartmental model used to fit first 3 min of 11C-acetate tracer activity data. Model assumes that tracer enters freely exchangeable tissue pool at rate of F x E, where F is myocardial blood flow rate and E is extraction fraction for acetate. Tracer in freely exchangeable tissue pool either leaves that compartment and enters metabolically trapped pool with rate constant K1 or is washed out as function of blood flow.





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